by Mickael | Dec 1, 2021 | current projects
Despite the importance of knowing a drug’s mechanism of action (MOA) for its success in clinical trials and for understanding its potential side effects, it is not a requirement for Food Drug Administration (FDA) approval. As a result, many drugs on the market...
by Mickael | Jun 12, 2018 | current projects
Development of proteomics tools Our team aims at bringing the power and flexibility of the R/Bioconductor statistical plateform to mass spectrometry based proteomics. The Bioconductor plateform is a repertory of softwares, data and annotation packages based on the R...
by Mickael | Jun 12, 2018 | current projects
Epigenomics In the past decade, the main strategy for genome-wide mapping of chromatin modifications, histone marks and interactions between DNA and proteins, has been ChIP followed by microarray analysis (ChIP-chip). Recent improvements in the efficiency, quality,...
by Mickael | Jun 12, 2018 | current projects
Kibio.science The Kibio.science project (link) is an online biohub portal that combines Elasticsearch, a fast search engine designed to manage very large amounts of data, and Siren, a web visualization plugin, thatcreates relational links between biological databases....
by Mickael | May 4, 2018 | current projects
Machine learning We use machine learning approaches in different projects to analyze omics data. We also develop machine learning tools to help biomarker signature identification from disease-derived omics datasets. Omics datasets are generally highly unbalanced,...
by Mickael | May 4, 2018 | current projects
Personalised Risk Stratification for Prevention and Early Detection of Breast Cancer (collaboration) Each year, over 22,000 Canadian women are diagnosed with breast cancer, a disease that will claim the lives of 5,000 of them. The routine screening program currently...
